🔗 Share this article Users Discontinuing Slimming Injections Gain Back Weight at a Quadrupled Rate Compared to People Using Diet and Exercise Weight management often requires long-term strategies. New research indicates that people who stop using popular weight-loss injections like Wegovy and Mounjaro can put back on reduced body mass far faster than those who halt traditional diet and exercise regimens. Published data in a prominent medical journal points out that while overweight people often shed about a fifth of their body weight while using the jabs, the mass is regained at an average rate of 0.8 kg per month after stopping. "Users using such drugs need to be informed of the risk of quick rebound weight gain when the therapy ends," cautioned lead investigator Dr. Susan Jebb. This pace of regain implies a reversion to original weight within about 18 months. Weighing Treatments The study, which reviewed dozens of trials involving over 9,000 of patients, compared the results of the injectable medications with older methods. Scientists note that people who lose weight through dieting usually see a more gradual creep back—approximately 0.1 kg a month—post-intervention. Understanding the Quick Rebound Nutrition scientists propose the mode of action of the jabs is key to understanding the heightened regain. The injections copy a natural hormone called glucagon-like peptide-1, which controls hunger. "Long-term administration of GLP-1 concentrations far above than the body's typical production may cause the body to generate a reduced amount of its own natural hormone, and could lessen sensitivity to its effects," said Dr. Adam Collins, a nutrition expert. "Stopping of this medication results in appetite is unsuppressed, making overeating much more probable." A Lifelong Condition? The NHS suggest the injections for individuals with obesity-related medical conditions, alongside prescribed lifestyle changes. Many experts say that, given the significant potential of weight regain, the treatment might need to be life-long. This opinion is echoed by drug manufacturers, who note that the findings "highlight the chronic character of excess weight," akin to managing diseases like high blood pressure. User Testimonies Users who have stopped the medication describe a sudden return of hunger. "It was like a switch that goes on and you become starving," described a patient. This challenge is exacerbated if users have not developed lasting lifestyle or habit modifications during treatment. Growing Interest Figures show that a significant number of people in the UK have tried weight-loss jabs in the last 12 months, with demand remaining high. Use is more common among females than men. The middle-aged demographic shows the greatest level of interest. A large proportion obtain the medications through private prescriptions rather than public health services. In conclusion, experts emphasize that while these medications are powerful agents for shedding pounds, they are not a permanent solution and maintained weight loss likely depends on combined lifestyle changes.
Weight management often requires long-term strategies. New research indicates that people who stop using popular weight-loss injections like Wegovy and Mounjaro can put back on reduced body mass far faster than those who halt traditional diet and exercise regimens. Published data in a prominent medical journal points out that while overweight people often shed about a fifth of their body weight while using the jabs, the mass is regained at an average rate of 0.8 kg per month after stopping. "Users using such drugs need to be informed of the risk of quick rebound weight gain when the therapy ends," cautioned lead investigator Dr. Susan Jebb. This pace of regain implies a reversion to original weight within about 18 months. Weighing Treatments The study, which reviewed dozens of trials involving over 9,000 of patients, compared the results of the injectable medications with older methods. Scientists note that people who lose weight through dieting usually see a more gradual creep back—approximately 0.1 kg a month—post-intervention. Understanding the Quick Rebound Nutrition scientists propose the mode of action of the jabs is key to understanding the heightened regain. The injections copy a natural hormone called glucagon-like peptide-1, which controls hunger. "Long-term administration of GLP-1 concentrations far above than the body's typical production may cause the body to generate a reduced amount of its own natural hormone, and could lessen sensitivity to its effects," said Dr. Adam Collins, a nutrition expert. "Stopping of this medication results in appetite is unsuppressed, making overeating much more probable." A Lifelong Condition? The NHS suggest the injections for individuals with obesity-related medical conditions, alongside prescribed lifestyle changes. Many experts say that, given the significant potential of weight regain, the treatment might need to be life-long. This opinion is echoed by drug manufacturers, who note that the findings "highlight the chronic character of excess weight," akin to managing diseases like high blood pressure. User Testimonies Users who have stopped the medication describe a sudden return of hunger. "It was like a switch that goes on and you become starving," described a patient. This challenge is exacerbated if users have not developed lasting lifestyle or habit modifications during treatment. Growing Interest Figures show that a significant number of people in the UK have tried weight-loss jabs in the last 12 months, with demand remaining high. Use is more common among females than men. The middle-aged demographic shows the greatest level of interest. A large proportion obtain the medications through private prescriptions rather than public health services. In conclusion, experts emphasize that while these medications are powerful agents for shedding pounds, they are not a permanent solution and maintained weight loss likely depends on combined lifestyle changes.